Seattle has a robust public transit system; you can get pretty much anywhere using an interlinked bus/light rail/ferry pass called ORCA. Passes can be purchased in advance or you can download the ORCA app and buy passes that way. Routes can be planned online, either using the ORCA website, Google maps, or https://onebusaway.org.
That said: all the public transit options are ADA compliant but the drivers are sometimes super impatient about dealing with people who need help. Also, Seattle is a city of hills, sometimes steep ones. The city founders bulldozed and reshaped the land to make it so that they could slide lumber downhill to the port. There are paths through the city that are more accessible than others but I can't vouch for how safe it is (or if those buildings are open) because I haven't personally walked that way in >2 years. You're probably better off figuring out where you're going, getting an Uber or Lyft to your destination, and conserving your energy for exploring your destination.
no subject
That said: all the public transit options are ADA compliant but the drivers are sometimes super impatient about dealing with people who need help. Also, Seattle is a city of hills, sometimes steep ones. The city founders bulldozed and reshaped the land to make it so that they could slide lumber downhill to the port. There are paths through the city that are more accessible than others but I can't vouch for how safe it is (or if those buildings are open) because I haven't personally walked that way in >2 years. You're probably better off figuring out where you're going, getting an Uber or Lyft to your destination, and conserving your energy for exploring your destination.